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ZANAFLEX

Generic Name: tizanidine (tye ZAN i deen)
Brand Names: Zanaflex
Zanaflex Capsules™ - (tizanidine hydrochloride)
Zanaflex® Tablets -(tizanidine hydrochloride)

Zanaflex is a short-acting muscle relaxer. It works by blocking nerve impulses (pain sensations) that are sent to your brain.

Zanaflex® (tizanidine hydrochloride) is a prescription medication used to treat spasticity. It belongs to a group of drugs known as alpha-2 adrenergic agonists.

This is a short-acting medication that does not provide around-the-clock relief, since each dose lasts for only three to six hours, and the medication can only be taken three times a day. However, Zanaflex can be useful for providing relief from spasticity at certain predictable times during the day.

Spasticity is the continual contraction of muscles. This can result in pain and loss of function, and can interfere with walking, speaking, and movement. Over time, the muscles may actually shorten, which can result in significant deformity, as well as severe loss of function. Spasticity is usually the result of damage to the brain or the spinal cord.

Zanaflex Uses
Zanaflex is licensed for the short-term treatment of spasticity. The medicine does not work continuously; each dosage lasts between three and six hours. Because this product has only been studied in adults, it is not approved for children or teens at this time. "Off-label" uses of Zanaflex include treating tension headaches, lower back pain, and trigeminal neuralgia.


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Related entries

  Product description   Safety information   Side Effects

Zanaflex Description
Tizanidine hydrochloride is a centrally acting a2-adrenergic agonist. Tizanidine hydrochloride, USP is a white to off-white, fine crystalline powder, which is odorless or with a faint characteristic odor. Tizanidine is slightly soluble in water and methanol; solubility in water decreases as the pH increases. Its chemical name is 5-chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiodiazole hydrochloride. Tizanidine’s molecular formula is C9H8ClN5S·HCl, its molecular weight is 290.2 and its structural formula is:

Tizanidine tablets, USP are supplied 4 mg tablets for oral administration. Tizanidine tablets are composed of the active ingredient, tizanidine hydrochloride (2.288 mg equivalent to 2 mg tizanidine base and 4.576 mg equivalent to 4 mg tizanidine base), and the following inactive ingredients: anhydrous lactose, colloidal silicon dioxide, microcrystalline cellulose, pregelatinized Starch and stearic acid.



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