Zocor Administration and Monitoring Parameters
Zocor (Simvastatin) Administration
NOTE: Patients receiving simvastatin therapy should also be placed on a standard cholesterol-lowering diet, and this diet should be continued throughout therapy. Serum lipoprotein concentrations should be determined periodically and dosage adjusted according to individual response and established treatment guidelines.
Oral Administration
- Administer without regard to food. However, avoid administration with grapefruit juice to avoid potential increases in drug serum concentrations.
- Because peak cholesterol synthesis occurs in the early morning hours, evening dosing is recommended.
Zocor (Simvastatin) Monitoring Parameters
- creatine phosphokinase (CPK)
- LFTs
- serum cholesterol profile
[ Last revised: 10/12/2004 2:54:00 PM ]
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