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Tramadol Administration

Oral Administration

Tramadol is administered with or without food.
Slow titration of tramadol to the effective analgesic dose (i.e., increase by 50 mg PO every 3 days) may decrease the incidence of nausea and vomiting.

Parenteral Administration _† (not available in the US)

Tramadol may be given intravenously, subcutaneously, or epidurally.
Intravenous tramadol 50 - 150 mg provides similar analgesia as 5 - 15 mg of morphine IV. When given epidurally, tramadol is 1/30 as potent as morphine.
Tramadol has been given as an IV bolus over 1 minute (100 mg diluted in 2 ml NS).

Rectal Administration _† (not available in the US)

Instruct patient on proper use of suppository.
Moisten the suppository with water prior to insertion. If suppository is too soft because of storage in a warm place, chill in the refrigerator for 30 minutes or run cold water over it before removing the wrapper.

_† non-FDA approved

[ Last revised: 9/12/2005 2:58:00 PM ]

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