Skelaxin Indications and Dosage

• muscle spasm

Skelaxin Indications and Dosage

For use as an adjunct to rest, physical therapy, and other measures for the relief of acute, painful musculoskeletal conditions (e.g., muscle spasm):
Oral dosage:
Adults and adolescents: 800 mg PO three times daily or four times daily.
Elderly: Avoid use in the elderly due to the potential for anticholinergic side effects, sedation, and weakness. Drug efficacy at doses tolerated in the elderly is questionable.
Children, infants, and neonates: Safe and effective use has not been established.

Maximum Dosage Limits:

• Adults: 3200 mg/day PO.
  
• Elderly: Not advised for use in the elderly due to potential anticholinergic effects.
  
• Adolescents: 3200 mg/day PO.
  
• Children: Safe and effective use has not been established.

Patients with hepatic impairment:
According to the manufacturer, metaxalone is contraindicated in patients with significant hepatic impairment.

Patients with renal impairment:
According to the manufacturer, metaxalone is contraindicated in patients with significant renal impairment.

Intermittent hemodialysis:
Not applicable. Metaxalone is contraindicated in patients with significant renal impairment.

[ Last revised: 12/8/2005 1:08:00 PM ]

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