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Sildenafil Administration, Monitoring Parameters, Chemical Structure
Oral Administration
Sildenafil may be taken between 0.5 and 4 hours before sexual activity. May be administered without regard to meals.
See Drug Interactions; certain medications (e.g., nitrates) should not be taken with sildenafil and the administration of other medications (e.g., alpha blockers) concurrently may require a sildenafil dosage adjustment.
Extemporaneous 2.5 mg/ml sildenafil oral suspension † :
With a mortar and pestle, grind thirty 25-mg sildenafil citrate tablets to a fine powder.
In a separate container, mix one of the following: 1) 150 ml of Ora-Sweet® with 150 mL of Ora-Plus®; or 2) 150 mL of Simple Syrup, NF with 150 mL of methylcellulose 1%.
Add a small amount of the mixture to the fine powder and mix into a uniform paste. Add geometric amounts of the vehicle to the almost desired volume while mixing. Transfer to a graduated cylinder and adjust to volume while mixing.
Place in amber plastic bottles. Shake well before each use. These oral suspensions are stable for 91 days when stored at 4 and 25 degrees C.
† non-FDA approved
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Sildenafil Monitoring Parameters
laboratory monitoring not necessary
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Chemical Structure For: Sildenafil
[ Last revised: 2/20/2006 1:16:00 PM ]
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