Scopolamine Indications and Dosage
- aspiration prophylaxis
- bradycardia
- cycloplegia induction
- iritis
- motion sickness
- mydriasis induction
- sedation induction
- uveitis
Scopolamine Indications and Dosage
For the prevention of nausea/vomiting due to motion sickness:
Topical dosage:
Adults and children > 12 years: 1 disc (1 mg delivered over 3 days) applied to skin behind ear 4 hours before antiemetic effects are needed. The disc may be left in place for three days. For a repeat dose, apply to the skin behind the opposite ear.
Oral dosage:
Adults and children > 12 years: 250 - 800 mcg PO 1 hour before antiemetic effect is needed.
Parenteral dosage:
Adults: The recommended dose is 0.3 - 0.6 mg SC, IM, or IV. May be repeated 3 - 4 times daily.
Children: The recommended dose is 0.006 mg/kg SC, IM, or IV as a single dose. Do not exceed 0.3 mg per dose. Dose may be repeated as needed every 6 - 8 hours.
For use in aspiration prophylaxis prior to anesthesia and intubation; for use as an anesthesia adjunct to reduce excitement, produce amnesia, and sedation induction during surgery; for treatment of bradycardia during surgery:
Parenteral dosage:
Adults: The recommended dose is 0.3 - 0.6 mg SC, IM, or IV as a single dose 45 - 60 minutes before induction of anesthesia.
Children 1 - 12 years: The recommended dose is 0.006 mg/kg SC, IM, or IV as a single dose. Do not exceed 0.3 mg per dose. Dose may be repeated as needed every 6 - 8 hours.
For cycloplegia induction or mydriasis induction during ophthalmologic examination:
Ophthalmic dosage:
Adults: Instill 1 - 2 drops of 0.25% solution in eye(s) 1 hour before refraction.
Children: Instill 1 drop of 0.25% solution in eye(s) 1 hour before refraction.
For the treatment of iritis or uveitis:
Ophthalmic dosage:
Adults: Instill 1 - 2 drops of 0.25% solution in affected eye(s) up to four times daily.
Children: Instill 1 drop of 0.25% solution in affected eye(s) once, twice, or three times daily.
Patients with renal impairment:
Specific guidelines for dosage adjustments in renal impairment are not available; it appears that no dosage adjustments are needed.
[ Last revised: 5/30/2006 12:04:00 PM ]
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