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Promethazine Monitoring Parameters, Administration and Chemical Structure

Promethazine Monitoring Parameters


  • CBC with differential
  • LFTs: baseline

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Promethazine Administration

Oral Administration


  • May be administered without regard to meals.

Rectal administration


  • Instruct patient on proper use of suppository (see Patient Information).
  • Moisten the suppository with water prior to insertion. If suppository is too soft because of storage in a warm place, chill in the refrigerator for 30 minutes or run cold water over it before removing the wrapper.

Parenteral administration


  • Promethazine should not be given subcutaneously or intra-arterially.
  • Visually inspect parenteral products for particulate matter and discoloration prior to administration whenever solution and container permit.

Intravenous injection:


  • The 50 mg/ml solution should not be given IV; for IM use only.
  • Infuse the appropriate dose into the tubing of a free flowing IV solution. Maximum IV concentration is 25 mg/ml. Further dilution (i.e., to concentrations < 25 mg/ml) may be required to minimize risk of thrombophlebitis. Maximum infusion rate is 25 mg/minute.

Intramuscular injection:


  • Inject deeply into a large muscle (i.e., upper outer quadrant of the gluteus maximus or lateral part of the thigh). Aspirate prior to injection to avoid injection into a blood vessel.

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Chemical Structure(s) For: Promethazine

[ Last revised: 2/25/2004 4:31:00 PM ]

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