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Meclizine (Antivert) Indications and Dosage


  • motion sickness
  • nausea/vomiting
  • vertigo

Meclizine (Antivert) Indications and Dosage

For the treatment of nausea/vomiting and dizziness associated with motion sickness:
Oral Dosage:
Adults and adolescents: The recommended dose is 25 - 50 mg PO one hour before travel. May repeat dose every 24 hours as needed.
Elderly: Start at the lowest adult dosage. Elderly patients are more sensitive to anticholinergic effects.
Children < 12 years: Not recommended.

For control of vertigo associated with vestibular system diseases:
Oral Dosage:
Adults and adolescents: The recommended dose is 25 - 100 mg/day PO in divided doses.
Elderly: Start at the lowest adult dosage. Elderly patients are more sensitive to anticholinergic effects.
Children < 12 years: Not recommended.

Maximum Dosage Limits:


  • Adults: 100 mg/day PO.
  • Elderly: 100 mg/day PO. The elderly are more sensitive to anticholinergic effects.
  • Adolescents: 100 mg/day PO.
  • Children < 12 years: Not recommended.

Patients with hepatic impairment:
Specific guidelines for dosage adjustments in hepatic impairment are not available.

Patients with renal impairment:
Specific guidelines for dosage adjustments in renal impairment are not available; it appears that no dosage adjustments are needed.

[ Last revised: 1/5/2003 8:12:00 PM ]

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