Trichuris trichiura
† non-FDA-approved indication
Mebendazole (Vermox) Indications and Dosage
The following organisms are generally considered susceptible to mebendazole in vitro: Ancylostoma duodenale; Angiostrongylus cantonensis; Ascaris lumbricoides; Capillaria philippinensis; Echinococcus granulosus; Enterobius vermicularis; Giardia lamblia; Gnathostoma spinigerum; Hymenolepis nana; Mansonella perstans; Necator americanus; Onchocerca volvulus; Strongyloides stercoralis; Taenia saginata; Taenia solium; Trichinella spiralis; Trichuris trichiura.
For the treatment of trichuriasis, ascariasis, hookworm infection, or mixed infections with these parasites:
Oral dosage:
Adults and children > 2 years: The recommended dose is 100 mg PO twice daily for 3 days. For resistant infections (i.e., helminth ova continue to appear in feces 3 - 4 weeks following initial therapy), a second course of therapy is recommended.
For the treatment of enterobiasis (pinworm infection):
Oral dosage:
Adults and children > 2 years: The recommended dose is 100 mg PO as a single dose.
For the treatment of hydatid cyst disease † :
NOTE: Use is not currently recommended by the manufacturer, but has been effective in a few cases.
Oral dosage:
Adults and children > 2 years: A dose of 40 mg/kg PO once daily for 1 - 6 months or longer has been used.
For the treatment of capillariasis † :
Oral dosage:
Adults and children > 2 years: A dose of 200 mg PO twice daily for 20 days has been used.
For the treatment of toxocariasis † (visceral larva migrans):
Oral dosage:
Adults: Doses of 200 - 400 mg/day PO in 2 divided doses for 5 days have been used.
For the treatment of trichinosis † :
Oral dosage:
Adults: Doses of 200 - 400 mg PO three times per day for 3 days, followed by 400 - 500 mg PO three times per day for 10 days have been used.
Patients with renal impairment:
No dosage adjustment needed.
† non-FDA-approved indication
[ Last revised: 4/10/2004 8:30:00 PM ]
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