Levbid (Hyoscyamine) Adverse Reactions
- anhidrosis
- blurred vision
- confusion
- constipation
- cycloplegia
- dizziness
- drowsiness
- dysgeusia
- dyspepsia
- dysphagia
- flushing
- headache
- ileus
- impotence
- insomnia
- mydriasis
- nausea/vomiting
- palpitations
- photophobia
- sinus tachycardia
- urinary retention
- weakness
- xerostomia
Levbid (Hyoscyamine) Adverse Reactions
Adverse reactions to hyoscyamine are primarily due to its anticholinergic activity and are usually reversible when therapy is discontinued. The frequency and severity of adverse reactions are generally dose related and may be alleviated by a reduction in the hyoscyamine dose, however, dosage reduction may also eliminate any potential therapeutic effects of the drug. The most frequent adverse reactions associated with hyoscyamine therapy may include anhidrosis, blurred vision, confusion, constipation, cycloplegia, dizziness, drowsiness, dysgeusia, dyspepsia, dysphagia, flushing, headache, ileus, impotence, mydriasis, nausea/vomiting, nervousness, palpitations, photophobia, sinus tachycardia, urinary retention or hesitancy, weakness, and xerostomia. In many patients, xerostomia is the dose-limiting adverse effect of anticholinergics. Saliva substitutes may be useful in patients who suffer this adverse effect. Insomnia and bloated feeling have also been reported. Infants, patients with Down’s syndrome, and children with spastic paralysis or brain damage may be more sensitive to the mydriatic and positive chronotropic effects of anticholinergics. In patients with gastric ulcer, hyoscyamine may delay gastric emptying and cause antral stasis.
[ Last revised: 5/29/2002 ]
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