Fexofenadine (Allegra) Indications and Dosage
- allergic rhinitis
- urticaria
Fexofenadine Indications and Dosage
For the treatment of allergic rhinitis:
Oral dosage (immediate-release tablets or capsules):
Adults including the elderly, and adolescents >= 12 years: 60 mg PO twice daily or 180 mg PO once daily.
Children 6 - 11 years: 30 mg PO twice daily.
For the treatment of chronic idopathic urticaria:
Oral dosage (immediate-release tablets or capsules):
Adults including the elderly, and adolescents >= 12 years: 60 mg PO twice daily or 180 mg PO once daily.
Children 6 - 11 years: 30 mg PO twice daily.
Maximum Dosage Limits:
- Adults: 180 mg/day PO.
- Elderly: 180 mg/day PO.
- Adolescents: 180 mg/day PO.
- Children 6 - 11 years: 60 mg/day PO.
- Children < 6 years: Safe and effective use has not been established.
Patients with hepatic impairment:
No dosage adjustment is recommended. The pharmacokinetics of fexofenadine are not substantially different in patients with hepatic disease.
Patients with renal impairment:
CrCl < 80 ml/min: Reduce starting dose to 60 mg PO once daily for adults, elderly and adolescents >= 12 years. Reduce to 30 mg PO once daily for children 6 - 11 years old.
Intermittent hemodialysis:
The effect of hemodialysis on the removal of fexofenadine is unknown. Hemodialysis did not effectively remove fexofenadine from blood (up to 1.7% removed) following terfenadine oral administration.
[ Last revised: 11/8/2005 3:06:00 PM ]
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