Ezetimibe Administration, Monitoring Parameters & Chemical Structure
Ezetimibe Administration
NOTE: Patients receiving ezetimibe therapy should also be placed on a standard cholesterol-lowering diet, and this diet should be continued throughout therapy. Serum lipoprotein concentrations should be determined periodically and dosage adjusted according to individual response and established NCEP treatment guidelines.
Oral Administration
- Ezetimibe may be administered with or without food.
- If taken with a HMG-CoA reductase inhibitor (’statin’), the daily dose of ezetimibe may be taken at the same time as the statin.
- If prescribed concurrently with a bile acid sequestrant, administer ezetimibe at least 2 hours before or 4 hours after a dose of the bile acid sequestrant.
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Ezetimibe Monitoring Parameters
- LFTs
- serum cholesterol profile
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Chemical Structure For: Ezetimibe
[ Last revised: 10/12/2004 2:54:00 PM ]
References
. Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. JAMA 2001;285:2486 - 2497.
. Grundy SM, Cleeman JI, Merz CN, et al. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. Circulation 2004;110:227 - 39.
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