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Esomeprazole (Nexium) Injection

What is Esomeprazole Injection?
ESOMEPRAZOLE (Nexium®) prevents the production of acid in the stomach. It reduces symptoms and prevents injury to the esophagus, stomach, or intestines in patients with gastroesophageal reflux disease (GERD) or ulcers and in those taking nonsteroidal anti-inflammatory (NSAID) drugs. Generic esomeprazole injection is not available.

What should my health care professional know before I take esomeprazole?
They need to know if you have any of these conditions:


  • liver disease
  • an unusual or allergic reaction to esomeprazole, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I take this medicine?
Esomeprazole injection is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?
This does not apply.

What drug(s) may interact with esomeprazole?


  • ampicillin
  • diazepam
  • digoxin
  • iron salts
  • itraconazole, ketoconazole, voriconazole, or other prescription medicines for fungus or yeast infections
  • phenytoin
  • warfarin

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from taking esomeprazole?
Side effects that you should report to your prescriber or health care professional as soon as possible:


  • chest pain or tightness
  • dark yellow or brown urine
  • shortness of breath
  • skin rash
  • unusual tiredness or fatigue

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):


  • headache
  • diarrhea or constipation
  • flatulence (gas)
  • nausea/vomiting
  • dry mouth

What should I watch for while taking esomeprazole?
It can take several days of therapy with esomeprazole before your stomach pains improve. Check with your prescriber or health care professional if your condition does not improve, or if it gets worse. You can take antacids for the occasional relief of pain unless your prescriber or health care professional tells you otherwise.

Where can I keep my medicine?
This does not apply. You will not be given esomeprazole injection to use at home.

[ Last Revised: 5/10/2005 9:38:00 AM ]

NOTE: This information is not intended to cover all possible uses, precautions, interactions, or adverse effects for this drug. If you have questions about the drug(s) you are taking, check with your health care professional.

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