Denavir (Penciclovir) Indications and Dosage
- herpes labialis
- herpes simplex virus type 1
- herpes simplex virus type 2
- varicella-zoster virus †
† non-FDA-approved indication
Denavir (Penciclovir) Indications and Dosage
The following viruses are generally considered susceptible to penciclovir in vitro: herpes simplex virus type 1; herpes simplex virus type 2; varicella-zoster virus † .
For the treatment of recurrent herpes labialis or herpes facialis:
Topical dosage:
Adults, adolescents, and children > 12 years: Apply 1% cream every 2 hours while awake for 4 days beginning within 1 hours of onset of symptoms (during the prodrome or when lesions appear).
Maximum Dosage Limits:
- Adults: No maximum dosage information is available.
- Elderly: No maximum dosage information is available.
- Adolescents: No maximum dosage information is available.
- Children < 12 years: Safe and effective use has not been established.
Patients with hepatic impairment:
No dosage adjustment is recommended for topical therapy. The pharmacokinetics of penciclovir have not been evaluated in patients with severe uncompensated hepatic impairment.
Patients with renal impairment:
No dosage adjustment needed for topical therapy.
[ Last revised: 10/29/2003 4:06:00 PM ]
Related entries
Syndicate
|
