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Colchicine injection

What is colchicine injection?
COLCHICINE treats joint pain and swelling due to gout. Colchicine relieves pain and reduces the inflammation of acute gouty arthritis. Generic colchicine injections are available.

What should my health care professional know before I receive colchicine?
They need to know if you have any of these conditions:


  • an alcohol abuse problem
  • blood disorders
  • dental disease
  • having intramuscular injections
  • heart disease
  • kidney disease
  • liver disease
  • stomach or intestinal disease
  • an unusual or allergic reaction to colchicine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?
Colchicine is for injection into a vein. It must not be injected by any other route. It is given by a health-care professional in a clinic or hospital setting for the treatment of an acute attack of gout. Once symptoms have improved you will probably be given tablets of colchicine to take by mouth.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?
This does not apply.

What drug(s) may interact with colchicine?


  • alcohol
  • antiinflammatory drugs (NSAIDs, such as ibuprofen)
  • clarithromycin
  • cyanocobalamin, vitamin B12
  • cyclosporine
  • erythromycin

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from receiving colchicine?
Side effects that you should report to your prescriber or health care professional as soon as possible:


  • blood in urine
  • difficulty breathing
  • fever, chills, or sore throat
  • muscle weakness
  • nausea, vomiting
  • numbness or tingling in hands or feet
  • pain or difficulty passing urine
  • pain, swelling, redness or irritation at the injection site
  • skin rash, itching
  • stomach pain
  • swelling of the face or mouth
  • unusual bruising or bleeding
  • unusual weakness or tiredness

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):


  • diarrhea
  • loss of appetite
  • hair loss

What should I watch for while taking colchicine?
Alcohol can increase the chance of getting stomach problems. It can also increase uric acid concentrations in the blood, which makes a gouty attack more likely. It is best to avoid alcoholic drinks.

Do not treat yourself with non-prescription pain-relievers without consulting your prescriber or health care professional.

Where can I keep my medicine?
Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F); do not freeze. Protect from light. Throw away any unused medicine after the expiration date.

[ Last Revised: 9/9/2005 4:42:00 PM ]

NOTE: This information is not intended to cover all possible uses, precautions, interactions, or adverse effects for this drug. If you have questions about the drug(s) you are taking, check with your health care professional.

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