Clobetasol (Temovate) Administration
NOTE: Best results are obtained when topical corticosteroids of adequate strength are used for specified lengths of time. Patients who fail to respond to clobetasol treatment after 1 - 4 weeks should be re-evaluated.
NOTE: Once control of the treated condition has been achieved, clobetasol treatment should be discontinued. Intermittent application of clobetasol may need to be continued to maintain remission or control of the treated condition in some cases. Some authorities recommend cyclic applications (i.e., 2 weeks of clobetasol treatment followed by 1 week of lubrication only) for chronic conditions like psoriasis. The lowest effective maintenance application should be used. Other options include changing to a less potent topical corticosteroid for maintenance and control of inflammation and symptoms.
Topical Administration
For topical dermatologic use only. Not for ophthalmic, oral, or intravaginal use. Clobetasol products are generally not recommended for use on the face or intertriginous areas.
Restrict application to the active lesions or affected areas and try to avoid normal surrounding skin.
The amount of cream or ointment needed to cover a certain area can be calculated. A 1 g application of cream covers 100 cm2 of skin. The entire skin surface of the average size adult will be covered by 30 g of topical steroid cream.
Clobetasol propionate preparations should not be used with occlusive dressings. Instruct patients not to bandage, cover, or wrap area in any way that may be occlusive.
Cream, emollient cream, gel, or ointment: Wash hands before and after application. Use gloves if required by universal precautions. Apply sparingly in a thin film and rub gently into affected area.
Scalp solution: Wash hands before and after application. Use gloves if required by universal precautions. Apply sparingly in a thin film to the affected areas of the scalp; rub in gently and completely.
Topical foam: Invert the can and dispense a small amount of foam(up to a maximum of a golf-ball-size dollop) into the cap of the can, onto a saucer or other cool surface, or directly on the lesion, taking care to avoid contact with the eyes. Dispensing directly onto hands is not recommended, as the foam will begin to melt immediately upon contact with warm skin. If applying to the scalp, move the hair away from the affected area of the scalp so that the foam can be applied. Gently massage into affected scalp area until the foam disappears. Repeat until entire affected area is treated. Wash hands before and after treatment.
Dental topical preparation † for application to oral vesiculoerosive disease: An extemporaneous preparation of clobetasol for buccal or oral mucous membrane application can be compounded by combining clobetasol propionate ointment in a 1:1 ratio with a plasticized hydrocarbon gel (Orabase™-plain). No stability data are currently available.
† non-FDA approved
[ Last revised: 1/19/2004 12:42:00 PM ]
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Clobetasol (Temovate) Monitoring Parameters
laboratory monitoring not necessary
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Chemical Structure For: Clobetasol
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