Carisoprodol (Soma) Indications and Dosage
Carisoprodol (Soma) Indications and Dosage
For treatment of painful musculoskeletal conditions including muscle spasm:
Oral dosage:
Adults and adolescents: The recommended dosage is 350 mg PO three times daily and at bedtime.
Elderly: Generally not recommended.
Children < 12 years: Safe and effective use has not been established.
Maximum Dosage Limits:
Adults: 1400 mg/day PO (manufacturer dosage limits for Soma®); up to 1600 mg/day PO recommended for carisoprodol combination products (e.g., Soma® Compound).
Elderly: Not recommended.
Adolescents: 1400 mg/day PO (manufacturer dosage limits for Soma®); up to 1600 mg/day PO recommended for carisoprodol combination products (e.g., Soma® Compound).
Children: Safe and effective use has not been established.
Patients with hepatic impairment:
Dosage reduction may be necessary based on clinical response and degree of hepatic impairment; carisoprodol is primarily metabolized by the liver.
Patients with renal impairment:
Dosage should be modified depending on clinical response and degree of renal impairment, but no quantitative recommendations are available. Metabolites, including meprobamate, are excreted renally.
† non-FDA-approved indication
[ Last revised: 4/1/2003 9:12:00 AM ]
References
. Beers MH. Explicit criteria for determining potential inappropriate medication use by the elderly: an update. Arch Intern Med 1997;157:1531 - 6.
. Fick DM, Cooper JW, Wade WE, et al. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med 2003;163:2716 - 24.
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