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Aspirin, ASA; Butalbital; Caffeine Indications and Dosage


  • headache
  • migraine
  • mild pain
  • moderate pain

non-FDA-approved indication

Aspirin, ASA; Butalbital; Caffeine Indications and Dosage

For the treatment of occasional tension headache, occasional migraine or co-existing migraine and tension-type headaches:

Oral dosage (tablets or capsules containing aspirin 325 mg, butalbital 50 mg, and caffeine 40 mg):

Adults and the elderly: 1 - 2 tablets or capsules PO every 4 hours as needed. Maximum of 6 tablets or capsules per day. NOTE: According to OBRA regulations, butalbital is not to be used in a nursing home patient unless started before admission to the nursing home or given as a single dose for a medical or dental procedure. Discontinuation of butalbital should be attempted in the nursing home patient.
Children: Safe and effective use not established.

For the treatment of mild pain and moderate pain not related to headaches where relaxant and sedative effects are desired:

Oral dosage (tablets or capsules containing aspirin 325 mg, butalbital 50 mg, and caffeine 40 mg):

Adults and the elderly: 1 - 2 tablets or capsules PO every 4 hours as needed. Maximum of 6 tablets or capsules per day. NOTE: According to OBRA regulations, butalbital is not to be used in a nursing home patient unless started before admission to the nursing home or given as a single dose for a medical or dental procedure. Discontinuation of butalbital should be attempted in the nursing home patient.
Children: Safe and effective use not established.

Maximum Dosage Limits:


  • Adults: 6 tablets or capsules/day PO.
  • Elderly: 6 tablets or capsules/day PO.
  • Adolescents: Safe and effective use not established.
  • Children: Safe and effective use not established.

Patients with hepatic impairment:
Patients with hepatic disease may be at increased risk of salicylate-induced adverse reactions; however, no quantitative dosage recommendations are available. This combination not recommended for patients with severe hepatic disease.

Patients with renal impairment:
Dosage should be modified depending on clinical response and degree of renal impairment; no quantitative recommendations are available.

non-FDA approved indication

[ Last revised: 11/24/2003 2:38:00 PM ]

References
. Gurvich T, Cunningham JA. Appropriate Use of Psychotropic Drugs in Nursing Homes. Am Fam Physician 2000;61:1437 - 46.

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