Allopurinol injection
What is Allopurinol (Zyloprim) injection?
ALLOPURINOL (Aloprim™) reduces the amount of uric acid the body makes. During chemotherapy for certain types of leukemia, lymphoma or solid tumors, large amounts of uric acid may be formed. Too much uric acid in the blood can cause damage to your kidneys. Allopurinol (Zyloprim) will help to decrease the amount of uric acid and help to prevent damage to your kidneys during chemotherapy. Generic allopurinol injection is available.
What should my health care professional know before I take allopurinol?
They need to know if you have any of these conditions:
- kidney disease
- liver disease
- an unusual or allergic reaction to allopurinol, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
- breast feeding
How should I take this medicine?
Allopurinol injection is given as infusion into a vein by a health care professional. Treatment usually begins 1-2 days before you begin chemotherapy and then continues during your chemotherapy treatment. Once your chemotherapy is stopped, usually, this medicine will be stopped also.
What if I miss a dose?
This does not apply.
What drug(s) may interact with allopurinol?
- amoxicillin or ampicillin
- azathioprine
- certain medicines used to treat gout
- certain types of water pills (diuretics)
- chlorpropamide
- cyclosporine
- mercaptopurine
- theophylline
- warfarin
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
What side effects may I notice from taking allopurinol?
Side effects to allopurinol are rare but some can be serious. Side effects that you should report to your prescriber or health care professional as soon as possible:
- any type of skin rash or itching
- any signs of an allergic reaction such as difficulty breathing, wheezing, swelling or irritation of the eyes, or swelling of the lips and mouth
- difficulty passing urine
- redness, blistering, peeling or loosening of the skin, including inside the mouth
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
What should I watch for while taking allopurinol?
Drink plenty of water (10 to 12 full glasses a day) while you are taking allopurinol. This will help to reduce stomach upset and reduce the risk of getting gout or kidney stones.
Call your prescriber or health care professional at once if you get a skin rash together with chills, fever, or sore throat; difficulty passing urine; irritation of the eyes; or swelling of the lips and mouth.
You may get drowsy. Do not drive, use machinery, or do anything that needs mental alertness until you know how allopurinol affects you.
Where can I keep my medicine?
You will receive allopurinol injection in a hospital, You will not need to take any of the medicine home with you.
[ Last Revised: 9/13/2004 10:40:00 AM ]
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