Cefoxitin Adverse Reactions
- abdominal pain
- agranulocytosis
- anaphylactoid reactions
- anemia
- angioedema
- aplastic anemia
- azotemia
- bleeding
- candidiasis
- cholestasis
- colitis
- diarrhea
- dyspnea
- elevated hepatic enzymes
- eosinophilia
- erythema multiforme
- exfoliative dermatitis
- fever
- flushing
- hemolytic anemia
- hyperbilirubinemia
- hypotension
- injection site reaction
- interstitial nephritis
- jaundice
- leukopenia
- maculopapular rash
- nausea/vomiting
- neutropenia
- pancytopenia
- phlebitis
- pruritus
- pseudomembranous colitis
- seizures
- serum sickness
- Stevens-Johnson syndrome
- superinfection
- thrombocytopenia
- toxic epidermal necrolysis
- urticaria
- vaginitis
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Inyección de cefoxitina
¿Qué es la inyección de cefoxitiña?
La CEFOXITINA (Mefoxin®) es un antibiótico. La cefoxitiña mata o detiene el crecimiento de bacterias que causan infecciónes. La cefoxitiña se utiliza en el tratamiento de muchos tipos de infecciónes incluyendo las de la piel, huesos, estómago, vías respiratorias, senos, sangre, oídos y tracto urinario. Aún no hay inyecciónes genéricas de cefoxitiña disponibles.
¿Qué le debo informar a mi profesional de la salud antes de tomar este medicamento?
Necesita saber si usted presenta alguno de los siguientes problemás o situaciones:
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Cefoxitin Monitoring Parameters and Chemical Structure
Cefoxitin Monitoring Parameters
- serum creatinine/BUN: baseline
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Cefoxitin Administration
Parenteral Administration
Administer intravenously or intramuscularly.
Do not use diluents containing benzyl alcohol for preparing doses for pediatric patients. Benzyl alcohol has been associated with toxicity in neonates and may also cause toxicity in some smaller pediatric patients.
Visually inspect parenteral products for particulate matter and discoloration prior to administration whenever solution and container permit.
Intramuscular injection:
Vials: reconstitute each gram with 2 ml of sterile water for injection. Alternatively, for IM use only, each gram may be reconstituted with 2 ml of 0.5% lidocaine HCl (without epinephrine) to minimize IM discomfort.
Inject appropriate dose deeply into a large muscle (i.e., upper outer quadrant of the gluteus maximus or lateral part of the thigh). Aspirate to avoid injection into a blood vessel.
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Cefoxitin Indications and Dosage
- Bacteroides fragilis
- Bacteroides sp.
- bone and joint infections
- cervicitis
- Clostridium sp.
- Eikenella corrodens
- endometritis
- Escherichia coli
- Fusobacterium sp.
- gonorrhea
- gynecologic infections
- Haemophilus influenzae (beta-lactamase negative)
- Haemophilus influenzae (beta-lactamase positive)
- intraabdominal abscess
- intraabdominal infections
- Klebsiella pneumoniae
- Klebsiella sp.
- lower respiratory tract infections
- lung abscess
- Morganella morganii
- Neisseria gonorrhoeae
- pelvic cellulitis
- pelvic inflammatory disease (PID)
- Peptococcus sp.
- Peptostreptococcus sp.
- peritonitis
- pneumonia
- proctitis
- Proteus mirabilis
- Proteus vulgaris
- Providencia rettgeri
- Salmonella sp.
- septicemia
- Shigella sp.
- skin and skin structure infections
- Staphylococcus aureus (MSSA)
- Staphylococcus epidermidis
- Streptococcus pneumoniae
- Streptococcus pyogenes (group A beta-hemolytic streptococci)
- surgical infection prophylaxis
- urethritis
- urinary tract infection (UTI)
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Cefoxitin Contraindications and Precautions
- cephalosporin hypersensitivity
- breast-feeding
- coagulopathy
- colitis
- GI disease
- intramuscular injections
- penicillin hypersensitivity
- pregnancy
- renal disease
- renal impairment
- viral infection
- vitamin K deficiency
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Cefoxitin Interactions
Aminoglycosides
Anticoagulants
- Chloramphenicol
Macrolides
- Polymyxin B
- Probenecid
Tetracyclines
- Vancomycin
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Cefoxitin (Mefoxin®)
Classification:
Antiinfective Agents
» Cephalosporins
» Second-generation cephalosporins
Description: Cefoxitin is a parenteral cephamycin antibiotic that is classified as a second-generation cephalosporin. The drug has added stability against the beta-lactamases, providing better resistance to certain gram-negative species. When it was marketed, cefoxitin was the first cephalosporin-like antibiotic to exhibit activity against anaerobes. Many institutions have substituted cefotetan for cefoxitin since their spectra of activity is extremely similar, and cefotetan can be dosed less frequently. In addition, cefoxitin has been found to be a potent inducer of beta-lactamases. Therapeutic uses of cefoxitin include soft-tissue and skin infections, intra-abdominal infection, obstetric/gynecologic infection, and respiratory and urinary tract infections. Cefoxitin was approved by the FDA in 1978.
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Cefoxitin injection
What is cefoxitin injection?
CEFOXITIN (Mefoxin®) is an antibiotic. Cefoxitin kills bacteria that cause infection, or stops the growth of bacteria. Cefoxitin treats many kinds of infections including those of the skin, bone, stomach, respiratory tract, blood, sinuses, ears, and urinary tract. Generic cefoxitin injections are not yet available.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
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