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IMITREX

Generic Name: sumatriptan (oral/nasal) (soo ma TRIP tan)
Brand Names: Imitrex, Imitrex Nasal

Imitrex (sumatriptan) is a headache medicine that narrows blood vessels around the brain. Imitrex also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.

Imitrex is used to treat migraine headaches. Imitrex will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.

Imitrex should not be used to treat a common tension headache, a headache that causes loss of movement on one side of your body, or any headache that seems to be different from your usual migraine headaches. Use this medication only if your condition has been confirmed by a doctor as migraine headaches.

Imitrex may also be used for purposes not listed in this medication guide.

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Product description

Safety information

Side Effects

What are the possible side effects of Imitrex (Sumatriptan)?

Sumatriptan (Oral/Nasal)
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using sumatriptan and call your doctor if you have a serious side effect such as:

chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling
sudden numbness or weakness, especially on one side of the body
sudden headache, confusion, problems with vision, speech, or balance
fast heart rate, agitation, muscle stiffness, hallucinations, lack of coordination, with nausea, vomiting, or diarrhea
sudden and severe stomach pain and bloody diarrhea
seizure (convulsions); or
numbness or tingling and a pale or blue-colored appearance in your fingers or toes

Less serious side effects may include:

nausea, vomiting, diarrhea
muscle pain
warmth or redness under your skin
pressure or heavy feeling in any part of your body
sneezing, runny nose, congestion, cough
burning, numbness, pain or other irritation in your nose or throat after using the nasal spray
unusual taste in your mouth after using the nasal spray
dizziness, sleepiness; or
drooling or sweating

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

Sumatriptan (Injection)
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using sumatriptan and call your doctor if you have a serious side effect such as:

chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling
wheezing, feeling short of breath
sudden numbness or weakness, especially on one side of the body
sudden headache, confusion, problems with vision, speech, or balance
agitation, hallucinations, fever, fast heart rate, muscle stiffness, nausea, vomiting, diarrhea, loss of coordination, fainting
sudden and severe stomach pain and bloody diarrhea
seizure (convulsions); or
numbness or tingling and a pale or blue-colored appearance in your fingers or toes

Less serious side effects may include:

muscle pain
warmth or redness under your skin
pressure or heavy feeling in any part of your body
feeling dizzy or sleepy; or
pain, redness, bleeding, swelling, or bruising where you injected the medicine

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Product description

Safety information

Side Effects

How should I take Imitrex (Sumatriptan)?

Sumatriptan (Oral/Nasal)
Use this medication exactly as it was prescribed for you. Do not use the medication in larger or smaller amounts, or use it for longer than recommended by your doctor. Overuse of migraine headache medicine can actually make your headaches worse. Follow the instructions on your prescription label.

Use sumatriptan as soon as you notice headache symptoms, or after an attack has already begun.

Your doctor may want to give your first dose of this medicine in a hospital or clinic setting to see if you have any serious side effects.

Take one sumatriptan tablet whole with a full glass of water. Do not split the tablet.

After taking a tablet: If your headache does not completely go away, or goes away and comes back, take a second tablet two (2) hours after the first. Do not take more than 200 mg of sumatriptan oral tablets in 24 hours. If your symptoms have not improved, contact your doctor before taking any more tablets.

Sumatriptan nasal spray comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions. Blow your nose to clear your nasal passages before using the nasal spray. Try not to sneeze or blow your nose just after using the spray.

After using the nasal spray: If your headache does not completely go away after using the spray, call your doctor before using a second spray of sumatriptan. If your headache goes away and then comes back, you may use a second spray if it has been at least two hours since you used the first spray. Do not use more than 40 mg of sumatriptan nasal spray in 24 hours. If your symptoms do not improve, contact your doctor before using any more sprays.

Contact your doctor if you have more than four headaches in one month (30 days).

Store sumatriptan at room temperature away from moisture, heat, and light.

Sumatriptan (Injection)
Sumatriptan is injected under the skin. Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Overuse of migraine headache medicine can actually make your headaches worse.

Your doctor may want to give your first dose of this medicine in a hospital or clinic setting to see if you have any serious side effects.

Sumatriptan injection comes in a vial (bottle), in a prefilled cartridge to be loaded into an autoinjector syringe (Imitrex Statdose), or in a needle-free injector device (Sumavel DosePro). Each vial, cartridge, or needle-free device is for one use only.

This medicine comes with patient instructions for injecting it. Your care provider will show you the best places on your body to inject the medication. Do not give yourself an injection if you do not understand these instructions. Ask your doctor or pharmacist if you have questions.

Use sumatriptan as soon as you notice headache symptoms, or after an attack has already begun.

After using an injection: If your headache does not completely go away after the injection, call your doctor before using a second sumatriptan injection. If your headache goes away and then comes back, you may use a second injection if it has been at least one hour since your first injection. Do not use more than two (2) injections in 24 hours. If your symptoms do not improve, contact your doctor before using any more injections.

Store at room temperature away from moisture, heat, and light. Throw away any unused medicine after the expiration date on the label has passed.

What happens if I overdose on Imitrex (Sumatriptan)?

Sumatriptan (Oral/Nasal)

Seek emergency medical attention if you think you have used too much of this medicine, or if anyone else has accidentally swallowed it.

Overdose symptoms may include tremors or shaking, skin redness, breathing problems, blue-colored lips or fingernails, vision problems, watery eyes or mouth, weakness, lack of coordination, or seizure (convulsions).

Sumatriptan (Injection)
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Product description

Safety information

Side Effects

What are the possible side effects of Imitrex (Sumatriptan)?

Sumatriptan (Oral/Nasal)
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using sumatriptan and call your doctor if you have a serious side effect such as:

chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling
sudden numbness or weakness, especially on one side of the body
sudden headache, confusion, problems with vision, speech, or balance
fast heart rate, agitation, muscle stiffness, hallucinations, lack of coordination, with nausea, vomiting, or diarrhea
sudden and severe stomach pain and bloody diarrhea
seizure (convulsions); or
numbness or tingling and a pale or blue-colored appearance in your fingers or toes

Less serious side effects may include:

nausea, vomiting, diarrhea
muscle pain
warmth or redness under your skin
pressure or heavy feeling in any part of your body
sneezing, runny nose, congestion, cough
burning, numbness, pain or other irritation in your nose or throat after using the nasal spray
unusual taste in your mouth after using the nasal spray
dizziness, sleepiness; or
drooling or sweating

Sumatriptan (Injection)
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using sumatriptan and call your doctor if you have a serious side effect such as:

chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling
wheezing, feeling short of breath
sudden numbness or weakness, especially on one side of the body
sudden headache, confusion, problems with vision, speech, or balance
agitation, hallucinations, fever, fast heart rate, muscle stiffness, nausea, vomiting, diarrhea, loss of coordination, fainting
sudden and severe stomach pain and bloody diarrhea
seizure (convulsions); or
numbness or tingling and a pale or blue-colored appearance in your fingers or toes

Less serious side effects may include:

muscle pain
warmth or redness under your skin
pressure or heavy feeling in any part of your body
feeling dizzy or sleepy; or
pain, redness, bleeding, swelling, or bruising where you injected the medicine

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.