DENAVIR

Use Denavir exactly as directed by your doctor. If you do not understand these directions, ask your doctor, nurse, or pharmacist to explain them to you.

Denavir should be applied to cold sore lesions every 2 hours while awake for a period of four days, unless otherwise directed by your doctor.

Denavir should be used to treat cold sores on the lips and face only.

For best results, treatment with this medication should begin as soon as possible after symptoms appear.

Do not apply Denavir to the inside of the nose or in or near the eyes, as it may cause irritation. Store this medication at room temperature away from moisture and heat.

HOW TO USE: Use this medication at the first sign of infection (such as tingling, burning, redness, or sores). Wash your hands with soap and water before and after applying this medication. Clean and dry the affected areas before applying the medication. Apply a thin layer of penciclovir cream to completely cover the area of the cold sore or the area of tingling/itching/redness/swelling, and rub in gently. Apply the cream every 2 hours (except during sleep) for 4 days or as directed by your doctor.Apply to skin only. Do not apply this medication in or near the eyes since this medication can irritate the eyes. If you do get medication in your eyes, flush with plenty of water. Do not apply inside the mouth or nose.Dosage is based on your medical condition and response to treatment. Do not use this drug more often or for longer than prescribed.Use this medication regularly to get the most benefit from it. This medication works best when the amount of drug absorbed by the skin stays at a constant level. Therefore, use this drug at evenly spaced intervals. To help you remember, use it at the same times each day.Cold sores (herpes) can spread easily. Penciclovir cream does not prevent the spread of herpes. Avoid close physical contact with others (such as kissing) during an outbreak until the cold sores have completely healed. Also, try not to touch the cold sore, and wash your hands if you do touch the cold sore.Tell your doctor if your condition persists or worsens after treatment is finished.

Do not apply penciclovir topical to the inside of the nose or in or near the eyes, as it may cause irritation.

For best results, treatment with penciclovir topical should begin as soon as possible after symptoms appear.

Serious side effects have not been reported with the use of Denavir.

Other less serious side effects may be more likely to occur. Continue to use this medication and talk to your doctor if you experience:

• headache;
• local numbness or tingling where the cream is applied;
• changes in taste;
• rash; or
• irritation at the application site.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.